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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATM All Species: 10.91
Human Site: T452 Identified Species: 26.67
UniProt: Q13315 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.33
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13315 NP_000042.3 3056 350687 T452 Q Q R H G E R T P Y V L R C L
Chimpanzee Pan troglodytes XP_001139487 3056 350692 T452 Q Q R H G E R T P Y V L R C L
Rhesus Macaque Macaca mulatta
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q62388 3066 349469 I451 Q Q R R G E R I P Y V L R C L
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001155872 3050 347768 T450 H Q R R G E R T P Y V L K C L
Frog Xenopus laevis Q9DE14 2654 301441 R193 S E N Q T Y L R C T Q F Q L L
Zebra Danio Brachydanio rerio XP_002667249 1913 215524
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q5EAK6 2767 317973 K306 L G V P V H E K W P Q T L L R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_001107666 3120 349933 Q462 H S K R S Q L Q S H V L S C L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M3G7 3856 435096 S1046 V R D E G K L S R K L I E C V
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7RZT9 2939 328678 R427 V Y A K N S Q R D R Q H L E D
Conservation
Percent
Protein Identity: 100 99.4 N.A. N.A. N.A. 83.8 N.A. N.A. N.A. 69.5 20.5 35.1 N.A. 22.1 N.A. N.A. 36.2
Protein Similarity: 100 99.7 N.A. N.A. N.A. 91.3 N.A. N.A. N.A. 82.8 39.9 46.3 N.A. 42.8 N.A. N.A. 56.7
P-Site Identity: 100 100 N.A. N.A. N.A. 86.6 N.A. N.A. N.A. 80 6.6 0 N.A. 0 N.A. N.A. 26.6
P-Site Similarity: 100 100 N.A. N.A. N.A. 86.6 N.A. N.A. N.A. 86.6 20 0 N.A. 0 N.A. N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. 23.9 N.A. 20.8
Protein Similarity: N.A. N.A. N.A. 42.5 N.A. 40.9
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. 0
P-Site Similarity: N.A. N.A. N.A. 53.3 N.A. 6.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 10 0 0 0 0 60 0 % C
% Asp: 0 0 10 0 0 0 0 0 10 0 0 0 0 0 10 % D
% Glu: 0 10 0 10 0 40 10 0 0 0 0 0 10 10 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % F
% Gly: 0 10 0 0 50 0 0 0 0 0 0 0 0 0 0 % G
% His: 20 0 0 20 0 10 0 0 0 10 0 10 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 10 0 0 0 10 0 0 0 % I
% Lys: 0 0 10 10 0 10 0 10 0 10 0 0 10 0 0 % K
% Leu: 10 0 0 0 0 0 30 0 0 0 10 50 20 20 60 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 10 0 10 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 10 0 0 0 0 40 10 0 0 0 0 0 % P
% Gln: 30 40 0 10 0 10 10 10 0 0 30 0 10 0 0 % Q
% Arg: 0 10 40 30 0 0 40 20 10 10 0 0 30 0 10 % R
% Ser: 10 10 0 0 10 10 0 10 10 0 0 0 10 0 0 % S
% Thr: 0 0 0 0 10 0 0 30 0 10 0 10 0 0 0 % T
% Val: 20 0 10 0 10 0 0 0 0 0 50 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % W
% Tyr: 0 10 0 0 0 10 0 0 0 40 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _